n The butterfat/milkfat part of milk which rises to the top; this part when separated from the remainder.
n (informal) frosting | Frosting, custard, creamer(,) or another substance similar to the oily part of milk or to whipped cream.
n (medicine) A viscous aqueous oil/fat emulsion with a medicament added, used to apply that medicament to the skin. (compare with ointment)